Alkyne-PEG-OH is widely used in bioconjugation and chemical synthesis due to its unique properties. The alkyne group allows for efficient click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), which is highly selective and reliable for attaching molecules. This makes it valuable in the development of drug delivery systems, where it can be used to link therapeutic agents to carriers like nanoparticles or polymers. In material science, it is employed to modify surfaces or create functionalized materials with specific properties. Additionally, it plays a role in biotechnological applications, such as labeling biomolecules for imaging or diagnostic purposes. Its PEG (polyethylene glycol) component enhances solubility and biocompatibility, making it suitable for use in biomedical and pharmaceutical research.