Alkyne-PEG-OH is widely used in bioconjugation and surface modification due to its unique chemical properties. The alkyne group enables click chemistry reactions, particularly with azides, allowing for efficient and selective coupling of molecules. This makes it valuable in the development of drug delivery systems, where it can be used to attach therapeutic agents to polymers or nanoparticles. In biomedical research, it is employed to functionalize surfaces or materials for biosensing, tissue engineering, and diagnostic applications. Its PEG (polyethylene glycol) component enhances solubility, reduces immunogenicity, and improves biocompatibility, making it suitable for use in vivo. Additionally, it is utilized in the synthesis of hydrogels and other biomaterials, where its reactivity and hydrophilic properties are advantageous.