1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)
99%
Reagent
Code: #96584
CAS Number
474922-22-0
blur_circular Chemical Specifications
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Molecular Information
Weight
2941.61 g/mol
Formula
C₁₃₉H₂₇₁N₄O₆₇P
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Storage & Handling
Storage
−20°C
description Product Description
This chemical is widely used in the development of drug delivery systems, particularly in the creation of liposomes and nanoparticles. It serves as a key component for surface modification, enabling the attachment of targeting ligands such as antibodies or peptides. This enhances the specificity of drug delivery to target cells or tissues, improving therapeutic efficacy while minimizing off-target effects. Additionally, it is utilized in bioconjugation techniques, where it facilitates the covalent bonding of biomolecules like proteins or drugs to polyethylene glycol (PEG) chains. This PEGylation process increases the stability and circulation time of therapeutic agents in the bloodstream, making it valuable in the formulation of long-acting pharmaceuticals. It is also employed in research for studying cell membrane interactions and developing advanced biomaterials.
format_list_bulleted Product Specification
Test Parameter | Specification |
---|---|
Appearance | Solid |
Purity | 98.5-100 |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
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1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)
This chemical is widely used in the development of drug delivery systems, particularly in the creation of liposomes and nanoparticles. It serves as a key component for surface modification, enabling the attachment of targeting ligands such as antibodies or peptides. This enhances the specificity of drug delivery to target cells or tissues, improving therapeutic efficacy while minimizing off-target effects. Additionally, it is utilized in bioconjugation techniques, where it facilitates the covalent bonding of biomolecules like proteins or drugs to polyethylene glycol (PEG) chains. This PEGylation process increases the stability and circulation time of therapeutic agents in the bloodstream, making it valuable in the formulation of long-acting pharmaceuticals. It is also employed in research for studying cell membrane interactions and developing advanced biomaterials.
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