1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)

99%

Reagent Code: #96584
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CAS Number 474922-22-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 2941.61 g/mol
Formula C₁₃₉H₂₇₁N₄O₆₇P
inventory_2 Storage & Handling
Storage −20°C

description Product Description

This chemical is widely used in the development of drug delivery systems, particularly in the creation of liposomes and nanoparticles. It serves as a key component for surface modification, enabling the attachment of targeting ligands such as antibodies or peptides. This enhances the specificity of drug delivery to target cells or tissues, improving therapeutic efficacy while minimizing off-target effects. Additionally, it is utilized in bioconjugation techniques, where it facilitates the covalent bonding of biomolecules like proteins or drugs to polyethylene glycol (PEG) chains. This PEGylation process increases the stability and circulation time of therapeutic agents in the bloodstream, making it valuable in the formulation of long-acting pharmaceuticals. It is also employed in research for studying cell membrane interactions and developing advanced biomaterials.

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Test Parameter Specification
Appearance Solid
Purity 98.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days $579.27
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (ammonium salt)
This chemical is widely used in the development of drug delivery systems, particularly in the creation of liposomes and nanoparticles. It serves as a key component for surface modification, enabling the attachment of targeting ligands such as antibodies or peptides. This enhances the specificity of drug delivery to target cells or tissues, improving therapeutic efficacy while minimizing off-target effects. Additionally, it is utilized in bioconjugation techniques, where it facilitates the covalent bonding of biomolecules like proteins or drugs to polyethylene glycol (PEG) chains. This PEGylation process increases the stability and circulation time of therapeutic agents in the bloodstream, making it valuable in the formulation of long-acting pharmaceuticals. It is also employed in research for studying cell membrane interactions and developing advanced biomaterials.
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