cis-2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethyl methanesulphonate

97%

Reagent Code: #121123
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CAS Number 67914-86-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 408.26 g/mol
Formula C₁₄H₁₅Cl₂N₃O₅S
badge Registry Numbers
EC Number 267-749-5
MDL Number MFCD06410887
thermostat Physical Properties
Boiling Point 615.5ºC
inventory_2 Storage & Handling
Density 1.59g/cm3
Storage room temperature

description Product Description

This compound is a key intermediate in the synthesis of Itraconazole, a triazole-class antifungal agent used in human medicine to treat systemic and superficial fungal infections, such as aspergillosis, candidiasis, and dermatophytosis. The cis configuration ensures stereospecificity in the pharmaceutical manufacturing process, where it is reacted to form the dioxolane ring system integral to the drug's structure. With high purity levels (typically 97%), it is valued in the pharmaceutical industry for producing effective, broad-spectrum antifungals that inhibit ergosterol biosynthesis in fungal cells, disrupting membrane integrity. Its role supports the development of medications that provide targeted therapy with minimal impact on human cells.

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Test Parameter Specification
Purity (%) 96.5-100%
Appearance White To Off-White Powder
Infrared Spectrum Conforms To Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿390.00
inventory 5g
10-20 days ฿770.00
inventory 25g
10-20 days ฿3,570.00

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