2-Chloro-4H-pyrido[1,2-a]pyrimidin-4-one
98%
Reagent
Code: #162470
CAS Number
5418-94-0
blur_circular Chemical Specifications
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Molecular Information
Weight
180.59 g/mol
Formula
C₈H₅ClN₂O
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Registry Numbers
MDL Number
MFCD00457859
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Physical Properties
Boiling Point
287°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, Inert Gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. It serves as a building block in medicinal chemistry due to its ability to engage in substitution reactions at the 2-chloro position, enabling the introduction of various functional groups. Its heterocyclic structure enhances binding affinity to biological targets, making it valuable in drug discovery programs focused on oncology and inflammatory diseases. Also employed in the preparation of fluorescent probes for biochemical assays owing to its rigid aromatic framework and photophysical properties.
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