4-[(S)-4-Boc-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidin-2(1H)-one

98%

Reagent Code: #232859
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CAS Number 2252403-85-1

science Other reagents with same CAS 2252403-85-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 606.6628 g/mol
Formula C₃₂H₃₆F₂N₆O₄
badge Registry Numbers
MDL Number MFCD32068509
thermostat Physical Properties
Boiling Point 703.6±70.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.33±0.1 g/cm3(Predicted)
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of targeted therapies for inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structural features enable selective modulation of JAK enzyme activity, contributing to reduced cytokine signaling and inflammation. The compound’s design supports improved pharmacokinetic properties, including metabolic stability and oral bioavailability, making it valuable in optimizing drug candidates for clinical use.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance Off-white to Gray Solid
Purity (%) 97.5-100%
LC-MS Conforms to Structure
NMR Conforms to Structure

Available Sizes & Pricing

Size Availability Unit Price Quantity
100mg
10-20 days ฿4,800.00
250mg
10-20 days ฿8,000.00
500mg
10-20 days ฿11,200.00
1g
10-20 days ฿16,000.00
4-[(S)-4-Boc-2-methyl-1-piperazinyl]-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methyl-3-pyridyl)pyrido[2,3-d]pyrimidin-2(1H)-one
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Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of targeted therapies for inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structural features enable selective modulation of JAK enzyme activity, contributing to reduced cytokine signaling and inflammation. The compound’s design supports improved pharmacokinetic properties, including metabolic stability and oral bioavailability, making it valuable in optimizin

Used as a key intermediate in the synthesis of Janus kinase (JAK) inhibitors, particularly in the development of targeted therapies for inflammatory and autoimmune diseases such as rheumatoid arthritis and psoriasis. Its structural features enable selective modulation of JAK enzyme activity, contributing to reduced cytokine signaling and inflammation. The compound’s design supports improved pharmacokinetic properties, including metabolic stability and oral bioavailability, making it valuable in optimizing drug candidates for clinical use.

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