JNJ31020028 is primarily investigated for its potential in neuroscience and mental health research. It is studied for its role as a selective antagonist of the neuropeptide Y Y2 receptor, which is implicated in regulating anxiety, stress, and mood disorders. Researchers explore its application in developing treatments for conditions such as anxiety, depression, and post-traumatic stress disorder (PTSD). Additionally, it is being examined for its effects on memory and cognitive function, offering potential therapeutic avenues for neurodegenerative diseases. Its ability to modulate specific neural pathways makes it a promising candidate for advancing psychiatric and neurological drug development.