SCH79797 dihydrochloride is primarily used in research settings as a potent and selective antagonist of protease-activated receptor 1 (PAR1), also known as thrombin receptor. Its application is significant in studying the role of PAR1 in various physiological and pathological processes, particularly in the context of thrombosis, inflammation, and cancer. Researchers utilize this compound to investigate the mechanisms of PAR1 signaling in cell proliferation, angiogenesis, and metastasis, providing insights into potential therapeutic targets. Additionally, it is employed in preclinical studies to explore its efficacy in preventing or treating conditions such as cardiovascular diseases, where PAR1 activation plays a critical role. Its use in experimental models helps in understanding the downstream effects of PAR1 inhibition and its potential as a drug candidate.