BQ-788 sodium salt is primarily used in research settings as a selective endothelin B (ETB) receptor antagonist. It is widely applied in studies investigating the role of endothelin receptors in various physiological and pathological processes. Researchers utilize it to block ETB receptor activity, helping to understand its involvement in vascular regulation, blood pressure control, and cardiovascular diseases. Additionally, it is employed in neuroscience research to explore the receptor's role in the central nervous system, including its impact on neurotransmission and neuroprotection. BQ-788 sodium salt is also used in pharmacological studies to evaluate the efficacy of endothelin-targeting drugs and to develop potential therapeutic strategies for conditions like pulmonary hypertension, heart failure, and kidney disorders. Its specificity makes it a valuable tool for dissecting the complex signaling pathways mediated by endothelin receptors.