AZD8797 is primarily used in research settings as a selective antagonist for the CX3CR1 receptor, which plays a significant role in immune responses and inflammation. Its application is focused on studying neuroinflammation and neurodegenerative diseases, such as Alzheimer's and multiple sclerosis, as it helps to modulate the activity of microglia, the brain's immune cells. Additionally, it is utilized in preclinical studies to explore its potential in reducing chronic inflammation and its effects on neuronal damage. Researchers also investigate its role in autoimmune disorders and its impact on the migration and activation of immune cells in various inflammatory conditions.