UCL 2077 is a selective blocker of small-conductance calcium-activated potassium channels (SK channels) primarily used in research settings to study its effects on neuronal excitability and signaling in the brain. It is particularly valuable for investigating the role of SK channels in neurological and psychiatric conditions such as epilepsy, anxiety, depression, and Parkinson's disease. Researchers utilize it to explore potential therapeutic pathways, develop new treatments targeting these disorders, and elucidate mechanisms of action in preclinical studies, including validating hypotheses related to ion channel function and electrochemical balance in the central nervous system.