TPMPA is primarily used as a selective antagonist for GABA_C receptors, making it a valuable tool in neuroscience research. It helps in studying the role of these receptors in the central nervous system, particularly in understanding visual processing, synaptic transmission, and neural circuitry. Researchers utilize TPMPA to block GABA_C receptor activity, enabling them to investigate its effects on retinal function and its potential implications in vision-related disorders. Additionally, it aids in differentiating the functions of GABA_C receptors from other GABA receptor subtypes, contributing to the development of targeted therapeutic strategies for neurological conditions.