MSX-130 is primarily used in the field of neuroscience research as a selective antagonist for certain glutamate receptors. It is particularly valuable in studies focused on understanding the role of these receptors in synaptic transmission and plasticity. By blocking specific receptor activity, MSX-130 helps researchers investigate the mechanisms underlying learning, memory, and neurological disorders such as epilepsy and neurodegenerative diseases. Its application extends to pharmacological experiments aimed at developing targeted therapies for conditions associated with glutamate receptor dysfunction. Additionally, MSX-130 is utilized in electrophysiological studies to dissect the contributions of specific receptor subtypes to neuronal signaling pathways.