Golgicide A is primarily used in biological research to study the Golgi apparatus, a crucial organelle in eukaryotic cells involved in processing and packaging proteins and lipids. It acts as a selective inhibitor of GBF1, a guanine nucleotide exchange factor, which disrupts the structure and function of the Golgi apparatus. This disruption helps researchers investigate the role of the Golgi in cellular processes such as secretion, membrane trafficking, and protein modification. Additionally, Golgicide A is utilized to explore the impact of Golgi dysfunction on diseases, including neurodegenerative disorders and cancer, providing insights into potential therapeutic targets. Its application is valuable in understanding cellular mechanisms and developing treatments for Golgi-related pathologies.