5-Chloro-2-methoxyphenylmagnesium bromide
0.50 M in 2-MeTHF
Reagent
Code: #166584
CAS Number
419535-75-4
blur_circular Chemical Specifications
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Molecular Information
Weight
245.79 g/mol
Formula
C₇H₆BrClMgO
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Registry Numbers
MDL Number
MFCD11113495
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key reagent in organic synthesis, particularly in the formation of carbon-carbon bonds through Grignard reactions. It reacts with electrophiles such as aldehydes, ketones, and esters to introduce the 5-chloro-2-methoxyphenyl group into target molecules. This makes it valuable in the synthesis of pharmaceutical intermediates and fine chemicals, especially in the development of active pharmaceutical ingredients (APIs) where chlorinated aromatic moieties are required. Its reactivity allows for efficient construction of complex molecular structures under anhydrous conditions. Commonly employed in research and industrial settings for scalable, selective transformations.
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