SB415286 is widely used in biochemical research as a potent and selective inhibitor of glycogen synthase kinase-3 (GSK-3). It plays a crucial role in studying cellular signaling pathways, particularly those involved in metabolism, cell proliferation, and differentiation. Researchers utilize SB415286 to investigate the impact of GSK-3 inhibition on conditions such as neurodegenerative diseases, diabetes, and cancer. Its application extends to understanding the regulation of Wnt signaling, which is critical in developmental biology and tissue homeostasis. Additionally, SB415286 is employed in experimental models to explore its potential therapeutic effects in mitigating pathological processes linked to GSK-3 activity.