(2'Z,3'E)-6-Bromoindirubin-3'-oxim
10mM in DMSO
Reagent
Code: #246468
CAS Number
667463-62-9
science Other reagents with same CAS 667463-62-9
blur_circular Chemical Specifications
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Molecular Information
Weight
356.17 g/mol
Formula
C₁₆H₁₀BrN₃O₂
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Registry Numbers
MDL Number
MFCD08705318
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Storage & Handling
Storage
-20°C
description Product Description
Used as a potent inhibitor of glycogen synthase kinase-3 (GSK-3) and cyclin-dependent kinases (CDKs), making it valuable in research on neurodegenerative diseases like Alzheimer's and cancer. It promotes neuronal survival and has shown anti-inflammatory and anti-proliferative effects in cellular models. Commonly applied in studies exploring stem cell differentiation and cell cycle regulation due to its ability to modulate key signaling pathways. Its oxime modification enhances solubility and stability, improving its utility in biological assays.
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