1-Bromo-2-cyclopropylethyne
95%
Reagent
Code: #172887
CAS Number
57951-72-1
blur_circular Chemical Specifications
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Molecular Information
Weight
145.00 g/mol
Formula
C₅H₅Br
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Registry Numbers
MDL Number
MFCD21332903
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as a specialty intermediate in organic synthesis, particularly in the preparation of acetylenic compounds for pharmaceuticals and agrochemicals. Its strained cyclopropyl group combined with the bromoalkyne functionality enables unique reactivity in coupling reactions, such as Sonogashira and Cadiot-Chodkiewicz, allowing construction of complex molecular architectures. It is also employed in the synthesis of bioactive molecules where the cyclopropylacetylene moiety enhances metabolic stability and binding affinity. Due to its reactivity, it is handled with care in controlled environments for research and development in medicinal chemistry.
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