tert-Butyl (3-bromo-5-iodophenyl)carbamate
97%
Reagent
Code: #151705
CAS Number
915413-42-2
blur_circular Chemical Specifications
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Molecular Information
Weight
398.038 g/mol
Formula
C₁₁H₁₃BrINO₂
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Registry Numbers
MDL Number
MFCD29920520
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Storage & Handling
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as an intermediate in pharmaceutical synthesis, particularly in the development of kinase inhibitors and other bioactive molecules. Its halogen substituents (bromine and iodine) allow for selective cross-coupling reactions, such as Suzuki or Buchwald-Hartwig aminations, enabling the construction of complex aromatic systems. The tert-butyl carbamate (Boc) group acts as a protected amine, facilitating stepwise synthesis in peptide-like structures or heterocyclic compounds. Commonly employed in medicinal chemistry for lead optimization due to its versatility in forming carbon-nitrogen and carbon-carbon bonds.
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