1-Bromo-2-(1,1-difluoroethyl)benzene
97%
Reagent
Code: #129300
CAS Number
444581-46-8
blur_circular Chemical Specifications
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Molecular Information
Weight
221.04 g/mol
Formula
C₈H₇F₂Br
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Registry Numbers
MDL Number
MFCD09996896
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Storage & Handling
Density
1.518 g/cm3 at 25 °C
Storage
Room temperature, seal, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions where a brominated aromatic compound is needed for coupling processes. Its difluoroethyl group contributes to enhanced metabolic stability and lipophilicity in bioactive molecules. Commonly employed in palladium-catalyzed cross-coupling reactions such as Suzuki or Heck reactions to construct complex organic frameworks. Also utilized in the development of fluorinated analogs of biologically active compounds, where the fluorine atoms influence binding affinity and pharmacokinetic properties.
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