2-Amino-5-Iodo-3-Methylbenzoic Acid
98%
Reagent
Code: #138846
CAS Number
108857-24-5
blur_circular Chemical Specifications
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Molecular Information
Weight
277.06 g/mol
Formula
C₈H₈INO₂
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a key intermediate in the synthesis of nonsteroidal anti-inflammatory drugs (NSAIDs), particularly in the development of selective COX-2 inhibitors. Its structure supports the construction of biologically active molecules due to the presence of both amino and carboxylic acid functional groups, allowing for peptide coupling and derivatization. The iodo substituent enables further modification through cross-coupling reactions such as Suzuki or Heck reactions, making it valuable in medicinal chemistry for creating diverse compound libraries. Also employed in the preparation of radiolabeled compounds for imaging and tracer studies, leveraging the iodine atom for isotopic labeling.
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