3,5-Bis(trifluoromethyl)benzoic acid
98%
Reagent
Code: #143397
Alias
3,5-bis(trifluoromethyl)benzoic acid
3,5-di-trifluoromethylbenzoic acid
3,5-bis(trifluoromethyl)benzoic acid
3,5-bistrifluoromethylbenzoic acid
CAS Number
725-89-3
blur_circular Chemical Specifications
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Molecular Information
Weight
258.12 g/mol
Formula
C₉H₄F₆O₂
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Registry Numbers
EC Number
211-970-1
MDL Number
MFCD00000388
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Physical Properties
Melting Point
142-143 °C(lit.)
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Storage & Handling
Density
1.42 g/cm3
Storage
Room temperature
description Product Description
Used as a key building block in pharmaceutical synthesis, particularly in the development of active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability due to the electron-withdrawing trifluoromethyl groups. Its structure is valuable in the design of drugs targeting central nervous system disorders and inflammatory conditions. Also employed in agrochemicals to improve the potency and environmental stability of pesticides and herbicides. Additionally, it serves as a ligand or intermediate in catalysis and coordination chemistry, especially in palladium-catalyzed cross-coupling reactions.
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