4-Bromo-2-(methylsulfonyl)benzoic Acid
≥95%
Reagent
Code: #172634
CAS Number
142994-02-3
blur_circular Chemical Specifications
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Molecular Information
Weight
279.11 g/mol
Formula
C₈H₇BrO₄S
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Registry Numbers
MDL Number
MFCD04037926
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of nonsteroidal anti-inflammatory drugs (NSAIDs) and selective COX-2 inhibitors. Its structure allows for effective derivatization, enabling the formation of esters, amides, and other functional groups important in drug design. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to the presence of both electron-withdrawing bromo and sulfonyl groups, which influence binding affinity and metabolic stability. Also utilized in the preparation of biologically active molecules targeting cancer and inflammatory diseases.
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