1-Bromo-4-methoxy-2-methyl-5-nitrobenzene
95%
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description Product Description
1-Bromo-4-methoxy-2-methyl-5-nitrobenzene is used as a specialty chemical intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly for developing active ingredients with substituted aromatic rings. The bromine substituent facilitates cross-coupling reactions (e.g., Suzuki, Heck), while the nitro group (ortho to methoxy, meta to bromine) enables reduction to amines or further electrophilic activations. The methoxy group provides ortho/para directing effects for electrophilic substitutions, and the methyl group influences steric and electronic properties. This compound is valuable in preparing dyes, fluorescent probes, and complex organic molecules in medicinal chemistry research, where precise control of electronic and steric factors is essential. Note: It is not typically suited for direct nucleophilic aromatic substitution on the bromine due to the meta position of the nitro group.
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