Tubastatin A is primarily used in research settings as a selective inhibitor of histone deacetylase 6 (HDAC6). Its application is significant in studying the role of HDAC6 in various cellular processes, particularly in the context of cancer, neurodegenerative diseases, and immune regulation. By inhibiting HDAC6, Tubastatin A helps researchers understand its impact on protein aggregation, cell motility, and stress response pathways. It is also explored for its potential therapeutic effects in conditions like Alzheimer's disease, where HDAC6 inhibition may reduce tau pathology and improve cognitive function. Additionally, Tubastatin A is utilized in studies related to inflammation and autoimmune disorders, as HDAC6 modulation can influence immune cell function and cytokine production. Its specificity for HDAC6 makes it a valuable tool in dissecting the biological roles of this enzyme and developing targeted therapies.