(-)-Trichostatin A is widely used in biomedical research as a potent histone deacetylase (HDAC) inhibitor. It is primarily employed to study epigenetic regulation, as it induces hyperacetylation of histones, leading to changes in gene expression. This compound is particularly valuable in cancer research, where it helps investigate the role of HDACs in tumor growth and differentiation. Additionally, it is utilized in stem cell studies to explore cellular reprogramming and differentiation processes. (-)-Trichostatin A also serves as a tool in neuroscience research to examine the epigenetic mechanisms underlying learning, memory, and neurodegenerative diseases. Its ability to modulate chromatin structure makes it a key reagent in understanding gene regulation and developing potential therapeutic strategies.