VER-49009 is primarily used in research settings as a potent inhibitor of heat shock protein 90 (Hsp90). Hsp90 is a chaperone protein that plays a critical role in the stabilization and activation of client proteins involved in cell signaling, proliferation, and survival. By inhibiting Hsp90, VER-49009 disrupts these processes, making it a valuable tool in studying cancer biology and exploring potential therapeutic strategies. Its application is particularly relevant in preclinical studies aimed at understanding the mechanisms of Hsp90 inhibition and its effects on tumor growth and survival. Additionally, VER-49009 is used to investigate the role of Hsp90 in other diseases where protein misfolding and degradation are implicated.