17-(Allylamino) Geldanamycin

98%

Reagent Code: #96299
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CAS Number 75747-14-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 585.69 g/mol
Formula C₃₁H₄₃N₃O₈
badge Registry Numbers
MDL Number MFCD04973892
inventory_2 Storage & Handling
Storage -20°C, protected from light

description Product Description

17-(Allylamino) Geldanamycin is primarily utilized in biomedical research due to its role as a heat shock protein 90 (Hsp90) inhibitor. This compound is instrumental in studying the mechanisms of protein folding and degradation, as Hsp90 is a crucial chaperone protein involved in stabilizing and activating a wide range of client proteins, many of which are implicated in cancer and other diseases. By inhibiting Hsp90, it helps researchers understand the pathways that lead to the degradation of oncogenic proteins, making it a valuable tool in the development of targeted cancer therapies. Additionally, it is used in preclinical studies to explore its potential efficacy in treating neurodegenerative diseases, where protein misfolding and aggregation are key pathological features. Its application extends to investigating cellular stress responses and the role of Hsp90 in maintaining cellular homeostasis under various conditions.

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Test Parameter Specification
Appearance Purple Powder
Purity (HPLC) 98-100
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿2,160.00
inventory 100mg
10-20 days ฿34,700.00
inventory 25mg
10-20 days ฿8,860.00

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