RU-SKI 43 hydrochloride (Hhat Inhibitor)

98%

Reagent Code: #109493
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CAS Number 1782573-67-4

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Weight 423.01 g/mol
Formula C₂₂H₃₁ClN₂O₂S
inventory_2 Storage & Handling
Storage -20°C, airtight, dry

description Product Description

RU-SKI 43 hydrochloride, as an Hhat inhibitor, is primarily used in research to study the role of protein palmitoylation in cellular processes. It specifically targets Hedgehog acyltransferase (Hhat), an enzyme involved in the palmitoylation of Hedgehog proteins, which are crucial for embryonic development and tissue regeneration. By inhibiting Hhat, this compound helps researchers understand the mechanisms of Hedgehog signaling pathways, which are often dysregulated in cancers such as basal cell carcinoma and medulloblastoma. Additionally, it serves as a tool to explore potential therapeutic strategies for diseases linked to aberrant Hedgehog signaling. Its application extends to drug discovery, where it aids in identifying and validating new targets for cancer treatment.

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Size Availability Unit Price Quantity
inventory 5mg
10-20 days ฿17,262.00
RU-SKI 43 hydrochloride (Hhat Inhibitor)
RU-SKI 43 hydrochloride, as an Hhat inhibitor, is primarily used in research to study the role of protein palmitoylation in cellular processes. It specifically targets Hedgehog acyltransferase (Hhat), an enzyme involved in the palmitoylation of Hedgehog proteins, which are crucial for embryonic development and tissue regeneration. By inhibiting Hhat, this compound helps researchers understand the mechanisms of Hedgehog signaling pathways, which are often dysregulated in cancers such as basal cell carcinoma and medulloblastoma. Additionally, it serves as a tool to explore potential therapeutic strategies for diseases linked to aberrant Hedgehog signaling. Its application extends to drug discovery, where it aids in identifying and validating new targets for cancer treatment.
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