Platelet dilution is primarily used in clinical and laboratory settings to prepare platelet-rich or platelet-poor plasma for diagnostic testing. It helps in standardizing platelet concentration for accurate coagulation studies, such as platelet function assays and aggregometry. By adjusting platelet levels, it ensures consistent results in tests evaluating bleeding disorders, thrombosis risk, or the effectiveness of antiplatelet therapies. It is also used in blood banking and transfusion medicine to optimize platelet counts in donated blood products before administration to patients.