Used as a selective herbicide in rice cultivation, particularly effective against broadleaf weeds and sedges, such as Cyperus species, during the early growth stages of rice. It is commonly applied in pre-emergence or early post-emergence treatments to control troublesome weeds in paddy fields. Its selectivity allows it to target weeds without significantly affecting rice seedlings when used at recommended rates. Cafenstrole acts by inhibiting the synthesis of very-long-chain fatty acids, disrupting lipid biosynthesis in susceptible weeds. Often included in integrated weed management programs, sometimes in mixtures with other herbicides, to reduce reliance on multiple applications, minimize weed competition, increase rice yield, and decrease manual labor.