4-((3-Chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-yl acetate

97%

Reagent Code: #118478
fingerprint
CAS Number 740081-22-5

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 361.76 g/mol
Formula C₁₇H₁₃ClFN₃O₃
badge Registry Numbers
MDL Number MFCD26395271
thermostat Physical Properties
Boiling Point 454.4±45.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, protected from light, stored in an inert gas

description Product Description

This compound serves as a key intermediate in medicinal chemistry, particularly in the synthesis of targeted cancer therapies such as tyrosine kinase inhibitors (TKIs). Featuring a quinazoline core substituted with a 3-chloro-2-fluorophenyl amino group at position 4, a methoxy group at 7, and an acetate at 6, it is used in the development of drugs that target enzymes involved in cell growth signaling pathways. These inhibitors can block tyrosine kinases to halt cancer cell proliferation, showing promise for treating cancers like non-small cell lung cancer. Its structure facilitates further derivatization, such as deprotection and addition of side chains, to produce more effective anticancer agents.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿270.00
inventory 250mg
10-20 days ฿459.00
inventory 1g
10-20 days ฿1,368.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB