Thalidomide-4-C3-NH2 hydrochloride is primarily utilized in research and pharmaceutical development due to its potential therapeutic properties. It is often studied for its anti-inflammatory, immunomodulatory, and anti-angiogenic effects, making it a candidate for treating conditions such as certain cancers, autoimmune diseases, and inflammatory disorders. Researchers explore its ability to inhibit the production of tumor necrosis factor-alpha (TNF-α) and its role in modulating the immune system. Additionally, its structural modifications, like the addition of the C3-NH2 group, are investigated to enhance its efficacy and reduce side effects compared to the parent compound, thalidomide. This compound is also used in the synthesis of more complex molecules for targeted drug delivery systems.