tert-Butyl 5-bromopyrimidine-2-carboxylate

96%

Reagent Code: #131585
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CAS Number 955885-59-3

science Other reagents with same CAS 955885-59-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 259.1 g/mol
Formula C₉H₁₁BrN₂O₂
badge Registry Numbers
MDL Number MFCD29764423
thermostat Physical Properties
Boiling Point 330.1±34.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.443±0.06 g/cm3(Predicted)
Storage 2-8°C, sealed, dry

description Product Description

Used as an intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrimidine derivatives. It serves as a building block in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The bromo substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the introduction of diverse molecular fragments. Its tert-butyl ester group provides stability during synthetic transformations and can be readily deprotected under acidic conditions to yield the corresponding carboxylic acid for further derivatization. Commonly employed in research settings for constructing complex heterocyclic systems in drug discovery programs.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿3,650.00
inventory 250mg
10-20 days ฿6,180.00
inventory 1g
10-20 days ฿16,660.00
tert-Butyl 5-bromopyrimidine-2-carboxylate
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Used as an intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrimidine derivatives. It serves as a building block in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The bromo substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the introduction of diverse molecular fragments. Its tert-butyl ester group provides stabili

Used as an intermediate in pharmaceutical synthesis, particularly in the preparation of biologically active pyrimidine derivatives. It serves as a building block in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The bromo substituent allows for further functionalization via cross-coupling reactions such as Suzuki or Buchwald-Hartwig aminations, enabling the introduction of diverse molecular fragments. Its tert-butyl ester group provides stability during synthetic transformations and can be readily deprotected under acidic conditions to yield the corresponding carboxylic acid for further derivatization. Commonly employed in research settings for constructing complex heterocyclic systems in drug discovery programs.

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