6-((2-chloro-5-fluoropyrimidin-4-yl)amino)-2,2-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one
97%
Reagent
Code: #191872
CAS Number
575473-90-4
science Other reagents with same CAS 575473-90-4
blur_circular Chemical Specifications
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Molecular Information
Weight
322.7221 g/mol
Formula
C₁₄H₁₂ClFN₄O₂
thermostat
Physical Properties
Boiling Point
516.4±50.0 °C(Predicted)
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Storage & Handling
Density
1.422±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in the development of anticancer agents. It plays a critical role in targeting epidermal growth factor receptor (EGFR) mutations, making it valuable in treatments for non-small cell lung cancer (NSCLC). The compound's structure allows for selective binding and improved pharmacokinetic properties in final drug formulations. It is primarily utilized in pharmaceutical research and development for creating targeted therapies with reduced side effects.
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