tert-Butyl 5-bromo-2-methyl-1H-benzo[d]imidazole-1-carboxylate
97%
Reagent
Code: #192454
CAS Number
1038392-63-0
science Other reagents with same CAS 1038392-63-0
blur_circular Chemical Specifications
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Molecular Information
Weight
311.17 g/mol
Formula
C₁₃H₁₅BrN₂O₂
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Registry Numbers
MDL Number
MFCD30067358
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors and antiviral agents. Its structure allows for selective functionalization at the bromo position, enabling coupling reactions such as Suzuki or Buchwald-Hartwig to introduce aromatic or heteroaromatic groups. The tert-butoxycarbonyl (Boc) protecting group stabilizes the imidazole nitrogen during multi-step syntheses and can be easily removed under mild acidic conditions when needed. Commonly employed in medicinal chemistry for constructing bioactive molecules targeting inflammation, cancer, and central nervous system disorders.
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