Methyl 5-iodo-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate
95%
Reagent
Code: #202894
CAS Number
116393-71-6
science Other reagents with same CAS 116393-71-6
blur_circular Chemical Specifications
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Molecular Information
Weight
296.02 g/mol
Formula
C₆H₅IN₂O₄
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Registry Numbers
MDL Number
MFCD12498716
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Storage & Handling
Density
2.17±0.1 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of antiviral and anticancer agents. Its structure allows for functionalization at multiple sites, making it valuable in medicinal chemistry for building pyrimidine-based heterocycles. Commonly employed in nucleoside analog synthesis, where the iodine moiety facilitates coupling reactions such as Suzuki or Stille cross-couplings. Also utilized in the preparation of kinase inhibitors and other biologically active molecules targeting cellular replication pathways. Its ester group enables further derivatization, enhancing solubility or bioavailability in drug design.