(Z)-2-(2-Aminothiazol-4-yl)-2-(tert-Butoxycarbonylmethoxyimino)acetic acid
98%
Reagent
Code: #246595
CAS Number
74440-02-1
science Other reagents with same CAS 74440-02-1
blur_circular Chemical Specifications
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Molecular Information
Weight
301.32 g/mol
Formula
C₁₁H₁₅N₃O₅S
thermostat
Physical Properties
Boiling Point
482.8°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used as a key intermediate in the synthesis of third-generation cephalosporin antibiotics, particularly in the production of ceftriaxone and similar beta-lactam antibiotics. Its structure allows for efficient coupling with other antibiotic moieties, enhancing antimicrobial activity and stability against beta-lactamase enzymes. Commonly employed in pharmaceutical manufacturing to introduce the aminothiazole oxime side chain, which improves penetration into bacterial cells and broadens the spectrum of activity against Gram-negative bacteria.
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