Used in histopathology to detect Helicobacter pylori in gastric tissue samples. The W-S method stain clearly visualizes the spiral or curvedform of H. pylori bacteria adhering to or near the gastric epithelium. It is particularly effective in highlighting the bacteria in biopsy specimens, aiding in the diagnosis of H. pylori-associated gastritis, peptic ulcers, and gastric cancer risk assessment. The staining technique provides high contrast, allowing for easy identification under light microscopy, even in cases with low bacterial load. It is commonly used in clinical laboratories and research settings where accurate detection of H. pylori is essential for patient management.