UNC0379 TFA is primarily utilized in biochemical and pharmacological research due to its role as a selective inhibitor. It specifically targets the enzyme lysine methyltransferase SETD8, which is involved in the regulation of histone methylation. This inhibition is crucial for studying cellular processes such as DNA repair, cell cycle regulation, and gene expression. Researchers employ UNC0379 TFA to explore its potential in cancer therapy, as inhibiting SETD8 can disrupt tumor growth and proliferation. Additionally, it serves as a valuable tool in epigenetics research, helping to elucidate the mechanisms of histone modification and its impact on cellular function and disease progression.