UNC0321 is primarily utilized in biochemical research as a potent and selective inhibitor of the enzyme G9a histone methyltransferase. This enzyme plays a critical role in the methylation of histone proteins, which is a key process in the regulation of gene expression. By inhibiting G9a, UNC0321 helps researchers study the effects of histone methylation on various cellular processes, including gene silencing, chromatin remodeling, and epigenetic regulation. Its application is particularly significant in the field of cancer research, where dysregulation of histone methylation is often observed. Additionally, UNC0321 is used to explore potential therapeutic strategies targeting epigenetic modifications in diseases such as neurological disorders and metabolic syndromes. The compound's high selectivity and potency make it a valuable tool for understanding the complex mechanisms of epigenetic control and for developing novel treatments based on epigenetic modulation.