(3R,5R,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid

≥98%

Reagent Code: #124645
fingerprint
CAS Number 1094100-06-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 481.54 g/mol
Formula C₂₂H₂₈FN₃O₆S
inventory_2 Storage & Handling
Storage 2-8°C, dry, sealed

description Product Description

This compound is the active pharmaceutical ingredient known as rosuvastatin, a statin drug widely used for managing high cholesterol levels (hypercholesterolemia) and preventing cardiovascular diseases. Its structure is crucial for inhibiting HMG-CoA reductase, the rate-limiting enzyme in cholesterol biosynthesis in the liver. By blocking this enzyme, rosuvastatin reduces the synthesis of LDL cholesterol and triglycerides while increasing HDL cholesterol, thereby lowering the risk of atherosclerosis, heart attacks, and strokes. The specific (3R,5R,E) stereochemistry and functional groups enhance its potency, selectivity, and pharmacokinetic profile, allowing for effective dosing with fewer side effects compared to earlier statins. It is typically prescribed under medical supervision due to potential adverse effects such as myopathy or hepatotoxicity.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10mg
10-20 days ฿30,294.00

Cart

No products

Subtotal: 0.00
Total 0.00 THB