Angiotensin III, human, plays a significant role in regulating blood pressure and fluid balance in the body. It is primarily involved in stimulating the release of aldosterone from the adrenal cortex, which helps in sodium retention and potassium excretion in the kidneys. This action contributes to maintaining blood volume and pressure. Additionally, it has been studied for its effects on vasoconstriction, which further influences blood pressure regulation. Research is ongoing to explore its potential therapeutic applications in conditions like hypertension and heart failure, where modulating its activity could provide clinical benefits.