Brain natriuretic peptide-32 (BNP-32) is primarily used in medical diagnostics and treatment. It serves as a biomarker for assessing heart failure, as elevated levels indicate cardiac stress or dysfunction. Clinically, BNP-32 tests aid in diagnosing, monitoring, and managing heart failure patients. It helps differentiate cardiac from non-cardiac causes of symptoms like shortness of breath. Additionally, synthetic BNP-32, known as nesiritide, is used therapeutically to treat acute decompensated heart failure by promoting vasodilation, reducing blood pressure, and improving cardiac output. Its applications are critical in cardiology for both diagnostic and therapeutic purposes.