Endothelin 2, human, plays a significant role in various physiological and pathological processes, particularly in the cardiovascular system. It is primarily involved in vasoconstriction, which helps regulate blood pressure and blood flow. This peptide is also studied for its impact on endothelial cell function, making it relevant in research related to hypertension, heart failure, and vascular diseases.

In cancer research, Endothelin 2 is explored for its role in tumor angiogenesis and metastasis, as it can influence the growth and spread of certain cancers. Additionally, it is investigated in reproductive biology for its effects on uterine contractions and placental function during pregnancy.

Pharmaceutical studies focus on developing endothelin receptor antagonists to treat conditions like pulmonary arterial hypertension and other vascular disorders. Its involvement in inflammation and fibrosis also makes it a target for therapeutic research in chronic inflammatory diseases and organ fibrosis. Overall, Endothelin 2, human, is a critical molecule in understanding and treating a range of medical conditions.