Used primarily in molecular biology and biochemistry labs, it serves as a key component in nucleic acid purification and precipitation processes. It helps stabilize and precipitate RNA and DNA during extraction procedures, ensuring high-quality samples for downstream applications like PCR, sequencing, and cloning. Additionally, it is employed in buffer preparation to maintain optimal pH conditions in enzymatic reactions, particularly those involving RNase-sensitive steps. Its RNase-free nature is critical for preventing RNA degradation, making it essential for RNA-related research and diagnostics.