1-Naphthohydrazide is primarily used in organic synthesis as a versatile intermediate for the preparation of various chemical compounds. It is often employed in the development of pharmaceuticals, particularly in the synthesis of hydrazone derivatives, which exhibit potential biological activities such as antimicrobial, anticancer, and anti-inflammatory properties. Additionally, it serves as a key reagent in the preparation of dyes and pigments, contributing to the coloration of textiles, plastics, and other materials. In analytical chemistry, 1-naphthohydrazide is utilized as a derivatization agent to enhance the detection and quantification of carbonyl compounds in complex mixtures. Its ability to form stable complexes with metal ions also makes it useful in coordination chemistry and metal ion extraction processes.