1,3-PBIT dihydrobromide is a potent and selective inhibitor of 15-lipoxygenase (15-LOX), an enzyme involved in arachidonic acid metabolism and the production of pro-inflammatory mediators. Primarily used in research settings, it helps investigate the role of 15-LOX in biochemical pathways related to inflammation, oxidative stress, cancer progression, and neurodegenerative processes. It is valuable for elucidating enzyme functions in cellular signaling, identifying therapeutic targets, and developing inhibitors for diseases such as certain cancers, inflammatory conditions, Parkinson's disease, and Alzheimer's disease. Additionally, it supports pharmacological studies on drug interactions and mechanisms of action.