ITSA-1 is primarily utilized in research and development within the field of biochemistry and molecular biology. It is known for its role as a potent and selective inhibitor of the enzyme indoleamine 2,3-dioxygenase 1 (IDO1). This enzyme is involved in the metabolism of tryptophan and plays a significant role in immune regulation. One of the key applications of ITSA-1 is in the study of cancer immunotherapy. By inhibiting IDO1, ITSA-1 helps to prevent the suppression of T-cell activity, thereby enhancing the immune system's ability to attack cancer cells. This makes it a valuable tool for researchers exploring new strategies to combat various types of cancer. Additionally, ITSA-1 is used in immunological studies to understand the mechanisms of immune tolerance and modulation. It provides insights into how IDO1 contributes to the immune evasion of tumors and the potential for therapeutic interventions. In summary, ITSA-1 is a critical compound in the investigation of cancer immunotherapy and immune system regulation, offering promising avenues for the development of novel treatments.