Used in biomedical research to detect and quantify Jo-1 autoantibodies (anti-histidyl-tRNA synthetase antibodies) in mouse serum or plasma samples. These autoantibodies are associated with autoimmune conditions such as polymyositis and dermatomyositis, particularly in models of idiopathic inflammatory myopathies. The ELISA kit enables researchers to monitor disease progression, assess immune response in experimental models, and evaluate the efficacy of therapeutic interventions targeting autoimmune pathways. It is a valuable tool in preclinical studies involving murine models of autoimmunity.